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Application of nano-graphene oxide as nontoxic disinfectant against alpha and betacoronaviruses.

ABSTRACT: New viruses are continuously emerging and recently there have been many great concerns on severe acute respiratory syndrome coronavirus (SARS-CoV-2). Nanographene oxide (nanoGO) has received much attention and is widely investigated to be utilised in therapy for infectious diseases by viruses. Thus, antiviral activity of nanoGO was evaluated using the porcine epidemic diarrhoea virus (PEDV), bovine coronavirus (BCoV), and SARS-CoV-2, which are all Alpha- and Beta-coronavirus. In a virus inhibition assay, the three viruses were inhibited by nanoGO in a dose-dependent manner, including attempts in the presence of high serum solution which partially mimicked biological fluid.

SUBMITTER: Chung HC 

PROVIDER: S-EPMC8604132 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature

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Application of nano-graphene oxide as nontoxic disinfectant against alpha and betacoronaviruses.

Chung Hee-Chun HC   Nguyen Van Giap VG   Kim Cheong Ung CU   Do Hai-Quynh HQ   Park Bong Kyun BK   Park Yong Ho YH   Song Dae-Sub DS   Kong Aeri A   Ryu Jae-Chul JC   Kang Kyung-Sun KS  

Veterinary medicine and science 20210727 6

New viruses are continuously emerging and recently there have been many great concerns on severe acute respiratory syndrome coronavirus (SARS-CoV-2). Nanographene oxide (nanoGO) has received much attention and is widely investigated to be utilised in therapy for infectious diseases by viruses. Thus, antiviral activity of nanoGO was evaluated using the porcine epidemic diarrhoea virus (PEDV), bovine coronavirus (BCoV), and SARS-CoV-2, which are all Alpha- and Beta-coronavirus. In a virus inhibiti  ...[more]