Efficacy and safety of electronic cigarettes as a smoking cessation intervention: A systematic review and network meta-analysis.

ABSTRACT:

Introduction

This systematic review of randomized controlled trials (RCTs) evaluated the efficacy and safety of electronic cigarettes (e-cigarettes, ENDS) in helping people who smoke to achieve abstinence compared with electronic non-nicotine delivery systems (ENNDS, no nicotine) or any smoking cessation comparator treatment or combination of treatments at 24-26 weeks and at 52 weeks.

Methods

Systematic review techniques involved searches of three databases in February 2020 with update searches run on 14 May 2021, two-person independent screening, two-person independent assessment of bias, formal extraction of data with verification by a second person, a feasibility assessment to decide if meta-analysis was appropriate, and network meta-analysis (NMA) of data at 24-26 weeks.

SUBMITTER: Quigley JM 

PROVIDER: S-EPMC8607936 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature