Nitric-oxide-driven oxygen release in anoxic Pseudomonas aeruginosa.
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ABSTRACT:
SUBMITTER: Lichtenberg M
PROVIDER: S-EPMC8608891 | biostudies-literature | 2021 Dec
REPOSITORIES: biostudies-literature
Publications
Nitric-oxide-driven oxygen release in anoxic <i>Pseudomonas aeruginosa</i>.
Lichtenberg Mads M Line Laura L Schrameyer Verena V Jakobsen Tim Holm TH Rybtke Morten Levin ML Toyofuku Masanori M Nomura Nobuhiko N Kolpen Mette M Tolker-Nielsen Tim T Kühl Michael M Bjarnsholt Thomas T Jensen Peter Østrup PØ
iScience 20211106 12
Denitrification supports anoxic growth of <i>Pseudomonas aeruginosa</i> in infections. Moreover, denitrification may provide oxygen (O<sub>2</sub>) resulting from dismutation of the denitrification intermediate nitric oxide (NO) as seen in <i>Methylomirabilis oxyfera</i>. To examine the prevalence of NO dismutation we studied O<sub>2</sub> release by <i>P. aeruginosa</i> in airtight vials. <i>P. aeruginosa</i> rapidly depleted O<sub>2</sub> but NO supplementation generated peaks of O<sub>2</sub> ...[more]
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