Validation and Update of the Lemann Index to Measure Cumulative Structural Bowel Damage in Crohn's Disease.

ABSTRACT:

Background & aims

The Lémann Index is a tool measuring cumulative structural bowel damage in Crohn's disease (CD). We reported on its validation and updating.

Methods

This was an international, multicenter, prospective, cross-sectional observational study. At each center, 10 inclusions, stratified by CD duration and location, were planned. For each patient, the digestive tract was divided into 4 organs, upper tract, small bowel, colon/rectum, anus, and subsequently into segments, explored systematically by magnetic resonance imaging and by endoscopies in relation to disease location. For each segment, investigators retrieved information on previous surgical procedures, identified predefined strictures and penetrating lesions of maximal severity (grades 1-3) at each organ inv

SUBMITTER: Pariente B 

PROVIDER: S-EPMC8609534 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature