Unknown

Dataset Information

0

Infigratinib: First Approval.


ABSTRACT: Infigratinib (TRUSELTIQTM), a fibroblast growth factor receptor (FGFR)-specific tyrosine kinase inhibitor, is being co-developed by QED Therapeutics and Helsinn for the treatment of cholangiocarcinoma, urothelial carcinoma and other FGFR-driven conditions. Infigratinib was recently approved in the USA for the treatment of previously treated, unresectable locally advanced or metastatic cholangiocarcinoma with a FGFR2 fusion or other rearrangement as detected by a test approved by the US Food and Drug Administration. This article summarizes the milestones in the development of infigratinib leading to this first approval for advanced cholangiocarcinoma.

SUBMITTER: Kang C 

PROVIDER: S-EPMC8610935 | biostudies-literature |

REPOSITORIES: biostudies-literature

Similar Datasets

| S-EPMC7062659 | biostudies-literature
| S-EPMC7044138 | biostudies-literature
| S-EPMC7459246 | biostudies-literature
| S-EPMC8519819 | biostudies-literature
| S-EPMC8748361 | biostudies-literature
| S-EPMC7471535 | biostudies-literature
| S-EPMC7522096 | biostudies-literature
| S-EPMC8010786 | biostudies-literature
| S-EPMC7595980 | biostudies-literature
| S-EPMC7983082 | biostudies-literature