Capacitive interdigitated system of high osteoinductive/conductive performance for personalized acting-sensing implants.

ABSTRACT: Replacement orthopedic surgeries are among the most common surgeries worldwide, but clinically used passive implants cannot prevent failure rates and inherent revision arthroplasties. Optimized non-instrumented implants, resorting to preclinically tested bioactive coatings, improve initial osseointegration but lack long-term personalized actuation on the bone-implant interface. Novel bioelectronic devices comprising biophysical stimulators and sensing systems are thus emerging, aiming for long-term control of peri-implant bone growth through biointerface monitoring. These acting-sensing dual systems require high frequency (HF) operations able to stimulate osteoinduction/osteoconduction, including matrix maturation and mineralization. A sensing-compatible capacitive stimulator of thin int

SUBMITTER: de Sousa BM 

PROVIDER: S-EPMC8611088 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature