ZnO Tips Dotted with Au Nanoparticles-Advanced SERS Determination of Trace Nicotine.

ABSTRACT: Long-term exposure to nicotine causes a variety of human diseases, such as lung damage/adenocarcinoma, nausea and vomiting, headache, incontinence and heart failure. In this work, as a surface-enhanced Raman scattering (SERS) substrate, zinc oxide (ZnO) tips decorated with gold nanoparticles (AuNPs) are fabricated and designated as ZnO/Au. Taking advantage of the synergistic effect of a ZnO semiconductor with morphology of tips and AuNPs, the ZnO/Au-based SERS assay for nicotine demonstrates high sensitivity and the limit of detection 8.9 × 10^-12 mol/L is reached, as well as the corresponding linear dynamic detection range of 10^-10-10^-6 mol/L. Additionally, the signal reproducibility offered by the SERS substrate could realize the reliable determination of

SUBMITTER: Cao J 

PROVIDER: S-EPMC8615426 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature