Ontology highlight
ABSTRACT:
SUBMITTER: Chen YF
PROVIDER: S-EPMC8616951 | biostudies-literature | 2021 Nov
REPOSITORIES: biostudies-literature
Chen Yen-Fu YF Hsieh Ao-Ho AH Wang Lian-Chin LC Huang Yun-Ju YJ Yun-Chen Tsai Tseng Wen-Yi WY Kuo Yu-Lun YL Luo Shue-Fen SF Yu Kuang-Hui KH Kuo Chang-Fu CF
Scientific reports 20211125 1
The association between the gut microbiota and the development of lupus is unclear. We investigated alterations in the gut microbiota after induction of lupus in a murine model using viral peptide of human cytomegalovirus (HCMV). Three treatment arms for the animals were prepared: intraperitoneal injection of HCMVpp65 peptide, adjuvant alone, and PBS injection. Feces were collected before and after lupus induction biweekly for 16S rRNA sequencing. HCMVpp65 peptide immunization induced lupus-like ...[more]