Unknown

Dataset Information

0

Association between Geriatric Nutrition Risk Index and The Presence of Sarcopenia in People with Type 2 Diabetes Mellitus: A Cross-Sectional Study.


ABSTRACT: The aim of this cross-sectional study was to examine the association between the geriatric nutritional risk index (GNRI) and the prevalence of sarcopenia in people with type 2 diabetes (T2DM). Having both low handgrip strength (<28 kg for men and <18 kg for women) and low skeletal muscle mass index (<7.0 kg/m2 for men and <5.7 kg/m2 for women) was diagnosed as sarcopenia. GNRI was estimated by the formula as below: GNRI = (1.489 × serum albumin level [g/L]) + (41.7 × [current body weight (kg)/ideal body weight (kg)]). Participants were dichotomized on the basis of their GNRI scores (GNRI < 98, low; or GNRI ≥ 98, high). Among 526 people (301 men and 225 women) with T2DM, the proportions of participants with sarcopenia and low GNRI were 12.7% (n = 67/526) and 5.1% (n = 27/526), respectively. The proportion of sarcopenia in participants with low-GNRI was higher than that with high GNRI (44.4% [n = 12/27] vs. 11.0% [n = 55/499], p < 0.001). The GNRI showed positive correlations with handgrip strength (r = 0.232, p < 0.001) and skeletal muscle mass index (r = 0.514, p < 0.001). Moreover, low GNRI was related to the prevalence of sarcopenia (adjusted odds ratio, 4.88 [95% confidence interval: 1.88-12.7], p = 0.001). The GNRI, as a continuous variable, was also related to the prevalence of sarcopenia (adjusted odds ratio, 0.89 [95% confidence interval: 0.86-0.93], p < 0.001). The present study revealed that low GNRI was related to the prevalence of sarcopenia.

SUBMITTER: Takahashi F 

PROVIDER: S-EPMC8618310 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature

altmetric image

Publications

Association between Geriatric Nutrition Risk Index and The Presence of Sarcopenia in People with Type 2 Diabetes Mellitus: A Cross-Sectional Study.

Takahashi Fuyuko F   Hashimoto Yoshitaka Y   Kaji Ayumi A   Sakai Ryosuke R   Kawate Yuka Y   Okamura Takuro T   Kitagawa Noriyuki N   Okada Hiroshi H   Nakanishi Naoko N   Majima Saori S   Senmaru Takafumi T   Ushigome Emi E   Asano Mai M   Hamaguchi Masahide M   Yamazaki Masahiro M   Fukui Michiaki M  

Nutrients 20211022 11


The aim of this cross-sectional study was to examine the association between the geriatric nutritional risk index (GNRI) and the prevalence of sarcopenia in people with type 2 diabetes (T2DM). Having both low handgrip strength (<28 kg for men and <18 kg for women) and low skeletal muscle mass index (<7.0 kg/m<sup>2</sup> for men and <5.7 kg/m<sup>2</sup> for women) was diagnosed as sarcopenia. GNRI was estimated by the formula as below: GNRI = (1.489 × serum albumin level [g/L]) + (41.7 × [curre  ...[more]

Similar Datasets

| S-EPMC9012026 | biostudies-literature
| S-EPMC11682223 | biostudies-literature
| S-EPMC7644336 | biostudies-literature
| S-EPMC9340875 | biostudies-literature
| S-EPMC9515181 | biostudies-literature
| S-EPMC5816962 | biostudies-literature
| S-EPMC10912133 | biostudies-literature
| S-EPMC11660792 | biostudies-literature
| S-EPMC10588858 | biostudies-literature
| S-EPMC9928854 | biostudies-literature