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ABSTRACT: Background
The outbreak of the COVID-19 epidemic has caused an unprecedented public health crisis and drastically impacted the economy. The relationship between different control measures and economic losses becomes a research hotspot.Methods
In this study, the SEIR infectious disease model was revised and coupled with an economic model to quantify this nonlinear relationship in Wuhan. The control measures were parameterized into two factors: the effective number of daily contacts (people) (r); the average waiting time for quarantined patients (day) (g).Results
The parameter r has a threshold value that if r is less than 5 (people), the number of COVID-19 infected patients is very close to 0. A "central valley" around r = 5~6 can be observed, indicating an optimal control measure to reduce economic losses. A lower value of parameter g is beneficial to stop COVID-19 spread with a lower economic cost.Conclusion
The simulation results demonstrate that implementing strict control measures as early as possible can stop the spread of COVID-19 with a minimal economic impact. The quantitative assessment method in this study can be applied in other COVID-19 pandemic areas or countries.
SUBMITTER: Chen X
PROVIDER: S-EPMC8621982 | biostudies-literature |
REPOSITORIES: biostudies-literature