Functionalized MoS₂ Nanoflowers with Excellent Near-Infrared Photothermal Activities for Scavenging of Antibiotic Resistant Bacteria.

ABSTRACT: Presently, antibiotic resistant bacteria (ARB) have been commonly found in environment, such as air, soil and lakes. Therefore, it is urgent and necessary to prepare antimicrobial agents with excellent anti-antibiotic resistant bacteria. In our research, poly-ethylene glycol functionalized molybdenum disulfide nanoflowers (PEG-MoS₂ NFs) were synthesized via a one-step hydrothermal method. As-prepared PEG-MoS₂ NFs displayed excellent photothermal conversion efficiency (30.6%) and photothermal stability. Under 808 nm NIR laser irradiation for 10 min, the inhibition rate of tetracycline-resistant Bacillus tropicalis and Stenotrophomonas malphilia reached more than 95% at the concentration of 50 μg/mL. More interestingly, the photothermal effect of PEG-MoS₂ NFs could accelerate the oxidation of glutathione, resulting in the rapid death of bacteria. A functionalized PEG-MoS₂ NFs photothermal anti-antibiotic resistant system was constructed successfully.

SUBMITTER: Liu L 

PROVIDER: S-EPMC8622428 | biostudies-literature |

REPOSITORIES: biostudies-literature