Environmental Pyrethroid Exposure and Cognitive Dysfunction in U.S. Older Adults: The NHANES 2001-2002.

ABSTRACT: Pyrethroid compounds are widely used in household insecticides and agricultural pesticides. Recent studies, however, report that pyrethroid exposures affect neurobehavioral function in animals and may be associated with adverse neurocognitive development in children. This study aimed to examine the association between pyrethroid exposure and cognitive dysfunction in older adults using a well-defined general population. We analyzed data from 336 individuals, aged 60-84 years, who participated in the National Health and Nutrition Examination Survey 2001-2002. We used urinary 3-phenoxybenzoic acid (3-PBA) concentration as a biomarker of pyrethroid exposures and assessed cognitive function with the digit-symbol coding test. The geometric means (±geometric standard errors) of creatinine-uncorre

SUBMITTER: Kim UJ 

PROVIDER: S-EPMC8623149 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature