Ontology highlight
ABSTRACT: Objectives
Men who have sex with men (MSM) are at risk of human papillomavirus (HPV)-related cancers, while published data are scarce. This study determined HPV prevalence and risk factors in MSM in Vietnam to inform HPV prevention strategies in this key population.Methods
A cross-sectional study of 799 MSM aged 16-50 years was conducted in Vietnam in 2017-2018. Information was collected on risk behaviours, and knowledge of HPV and anal cancer; rectal swabs were taken to detect anal HPV infection. An in-house polymerase chain reaction and Genoflow HPV array test kit were used for HPV detection and genotyping.Results
The median age of the study participants was 25 years (range 18-52). Overall prevalence of any HPV and HPV16/18 infection was 32.3% and 11.0%, respectively. A higher prevalence of high-risk HPV infection to all 14 types tested was found in Ho Chi Minh City (30.9%) than in Hanoi (18.4%). High-risk HPV infection was associated with inconsistent condom use and history of engaging in sex under the influence of drugs (adjusted odds ratio (aOR), 2.27; 95% CI, 1.48-10.67), as well as having multiple sexual partners (aOR, 1.01; 95% CI, 1.00-1.02).Conclusions
High-risk anal HPV infections in Vietnamese MSM were significantly associated with risky sexual behaviours. A targeted HPV vaccination strategy would have substantial benefit for MSM in Vietnam.
SUBMITTER: Tuan LA
PROVIDER: S-EPMC8627386 | biostudies-literature | 2021 Nov
REPOSITORIES: biostudies-literature
Tuan Le Anh LA Prem Kiesha K Pham Quang Duy QD Toh Zheng Quan ZQ Tran Hau Phuc HP Nguyen Phuc Duy PD Mai Chu Thi Ngoc CTN Ly Le Thi Khanh LTK Cao Van V Le-Ha Tam-Duong TD Tuan Nguyen Anh NA Jit Mark M Bright Kathryn K Brisson Marc M Nguyen Thuong Vu TV Garland Suzanne S Anh Dang Duc DD Trang Nguyen Van NV Mulholland Kim K
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases 20210910
<h4>Objectives</h4>Men who have sex with men (MSM) are at risk of human papillomavirus (HPV)-related cancers, while published data are scarce. This study determined HPV prevalence and risk factors in MSM in Vietnam to inform HPV prevention strategies in this key population.<h4>Methods</h4>A cross-sectional study of 799 MSM aged 16-50 years was conducted in Vietnam in 2017-2018. Information was collected on risk behaviours, and knowledge of HPV and anal cancer; rectal swabs were taken to detect a ...[more]