Ontology highlight
ABSTRACT:
SUBMITTER: Fernando ME
PROVIDER: S-EPMC8627701 | biostudies-literature | 2016 Jan
REPOSITORIES: biostudies-literature
Fernando Malindu E ME Seneviratne Ridmee M RM Tan Yong Mong YM Lazzarini Peter A PA Sangla Kunwarjit S KS Cunningham Margaret M Buttner Petra G PG Golledge Jonathan J
The Cochrane database of systematic reviews 20160113 1
<h4>Background</h4>The estimated likelihood of lower limb amputation is 10 to 30 times higher amongst people with diabetes compared to those without diabetes. Of all non-traumatic amputations in people with diabetes, 85% are preceded by a foot ulcer. Foot ulceration associated with diabetes (diabetic foot ulcers) is caused by the interplay of several factors, most notably diabetic peripheral neuropathy (DPN), peripheral arterial disease (PAD) and changes in foot structure. These factors have bee ...[more]