Ontology highlight
ABSTRACT:
SUBMITTER: Liu WM
PROVIDER: S-EPMC8630579 | biostudies-literature | 2021
REPOSITORIES: biostudies-literature
Liu Wen-Ming WM Zhou Xu X Chen Cai-Yang CY Lv Dong-Dong DD Huang Wei-Jian WJ Peng Yuan Y Wu Hong-Ping HP Chen Yi Y Tang Dan D Guo Li-Na LN Wang Xiu-Li XL Zhang Hong-Dan HD Liu Xiao-Hua XH Yang Li-Qun LQ Yu Wei-Feng WF Yan He-Xin HX
Frontiers in bioengineering and biotechnology 20211108
Globally, about two million people die from liver diseases every year. Liver transplantation is the only reliable therapy for severe end-stage liver disease, however, the shortage of organ donors is a huge limitation. Human hepatocytes derived liver progenitor-like cells (HepLPCs) have been reported as a novel source of liver cells for development of <i>in vitro</i> models, cell therapies, and tissue-engineering applications, but their functionality as transplantation donors is unclear. Here, a ...[more]