CCT4 suppression inhibits tumor growth in hepatocellular carcinoma by interacting with Cdc20.
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ABSTRACT:
SUBMITTER: Li F
PROVIDER: S-EPMC8631418 | biostudies-literature | 2021 Nov
REPOSITORIES: biostudies-literature
Publications
CCT4 suppression inhibits tumor growth in hepatocellular carcinoma by interacting with Cdc20.
Li Feng F Liu Chun-Sheng CS Wu Ping P Ling An-Sheng AS Pan Qi Q Li Xiao-Ning XN
Chinese medical journal 20211103 22
<h4>Background</h4>The chaperonin containing t-complex (CCT) proteins play an important role in cell cycle-related protein degradation in yeast and mammals. The role of the chaperonin containing t-complex 4 (CCT4), one subtype of CCT proteins, in the progress of hepatocellular carcinoma (HCC) was not fully elucidated. Here, we aimed to explore the mechanisms of CCT4 in HCC.<h4>Methods</h4>In this study, we used the UALCAN platform to analyze the relationship between CCT4 and HCC, and the associa ...[more]
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