Ontology highlight
ABSTRACT:
SUBMITTER: Palau-Rodriguez M
PROVIDER: S-EPMC8631729 | biostudies-literature | 2021 May
REPOSITORIES: biostudies-literature
Palau-Rodriguez Magalí M Marco-Ramell Anna A Casas-Agustench Patricia P Tulipani Sara S Miñarro Antonio A Sanchez-Pla Alex A Murri Mora M Tinahones Francisco J FJ Andres-Lacueva Cristina C
Journal of proteome research 20210324 5
Alterations in visceral adipose tissue (VAT) are closely linked to cardiometabolic abnormalities. The aim of this work is to define a metabolic signature in VAT of insulin resistance (IR) dependent on, and independent of, obesity. An untargeted UPLC-Q-Exactive metabolomic approach was carried out on the VAT of obese insulin-sensitive (IS) and insulin-resistant subjects (<i>N</i> = 11 and <i>N</i> = 25, respectively) and nonobese IS and IR subjects (<i>N</i> = 25 and <i>N</i> = 10, respectively). ...[more]