Neutrophil Extracellular Traps in Digestive Cancers: Warrior or Accomplice.
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ABSTRACT:
SUBMITTER: Chen Y
PROVIDER: S-EPMC8639597 | biostudies-literature | 2021
REPOSITORIES: biostudies-literature
Publications
Neutrophil Extracellular Traps in Digestive Cancers: Warrior or Accomplice.
Chen Yuxin Y Han Lulu L Qiu Xiaoyan X Wang Gang G Zheng Junnian J
Frontiers in oncology 20211119
Characterized as a complex of extracellular DNA fibers and granule proteins, neutrophil extracellular traps (NETs) are generated specifically by neutrophils which play a critical role in host defense and immune regulation. NETs have been initially found crucial for neutrophil anti-microbial function. Recent studies suggest that NETs are involved in tumorigenesis and cancer progression. However, the function of NETs in cancer remains unclear, which might be due to the variation of research models ...[more]
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