Age-Adjusted D-Dimer in the Prediction of Pulmonary Embolism: Systematic Review and Meta-analysis.

ABSTRACT:

Background

Pulmonary embolism (PE), depending on the severity, carries a high mortality and morbidity. Proper evaluation, especially in patients with low probability for PE, is important to avoid unnecessary diagnostic testing.

Objective

To review the diagnostic utility of conventional versus age-adjusted D-dimer cutoff values in patients 50 years and older with suspected pulmonary embolism.

Methods

Systematic review with univariant and bivariant meta-analysis.

Data sources

We searched PubMed, MEDLINE, and EBSCO for studies published before September 20th, 2020. We cross checked the reference list of relevant studies that compares conventional versus age-adjusted D-dimer cutoff values in patients with suspected pulmonary embolism.

Study selection

We incl

SUBMITTER: Iwuji K 

PROVIDER: S-EPMC8640977 | biostudies-literature | 2021 Jan-Dec

REPOSITORIES: biostudies-literature