New challenges in the combination of radiotherapy and immunotherapy in non-small cell lung cancer.

ABSTRACT: Immunotherapy has represented one of the main medical revolutions of recent decades, and is currently a consolidated treatment for different types of tumors at different stages and scenarios, and is present in a multitude of clinical trials. One of the diseases in which it is most developed is non-small cell lung cancer. The combination of radiotherapy and immunotherapy in cancer in general and lung cancer in particular currently represents one of the main focuses of basic and clinical research in oncology, due to the synergy of this interaction, which can improve tumor response, resulting in improved survival and disease control. In this review we present the biochemical and molecular basis of the interaction between radiotherapy and immunotherapy. We also present the current clinical sta

SUBMITTER: Luna J 

PROVIDER: S-EPMC8641011 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature