Ontology highlight
ABSTRACT: Motivation
Deciphering nucleosome-nucleosome interactions is an important step towards mesoscale description of chromatin organization but computational tools to perform such analyses are not publicly available.Results
We developed iNucs, a user-friendly and efficient Python-based bioinformatics tool to compute and visualize nucleosome resolved interactions using standard pairs format input generated from pairtools.Availability
https://github.com/Karimi-Lab/inucs/.Supplementary information
Supplementary data are available at Bioinformatics online.
SUBMITTER: Oveisi M
PROVIDER: S-EPMC8652021 | biostudies-literature | 2021 Oct
REPOSITORIES: biostudies-literature
Oveisi Mehrdad M Shukla Manu M Seymen Nogayhan N Ohno Masae M Taniguchi Yuichi Y Nahata Sunil S Loos Remco R Loos Remco R Mufti Ghulam J GJ Allshire Robin C RC Dimitrov Stefan S Karimi Mohammad M MM
Bioinformatics (Oxford, England) 20211201 23
<h4>Motivation</h4>Deciphering nucleosome-nucleosome interactions is an important step toward mesoscale description of chromatin organization but computational tools to perform such analyses are not publicly available.<h4>Results</h4>We developed iNucs, a user-friendly and efficient Python-based bioinformatics tool to compute and visualize nucleosome-resolved interactions using standard pairs format input generated from pairtools.<h4>Availabilityand implementation</h4>https://github.com/Karimi-L ...[more]