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CNN-PepPred: An open-source tool to create convolutional NN models for the discovery of patterns in peptide sets. Application to peptide-MHC class II binding prediction.


ABSTRACT:

Summary

The ability to unveil binding patterns in peptide sets has important applications in several biomedical areas, including the development of vaccines. We present an open-source tool, CNN-PepPred, that uses convolutional neural networks to discover such patterns, along with its application to peptide-HLA class II binding prediction. The tool can be used locally on different operating systems, with CPUs or GPUs, to train, evaluate, apply and visualize models.

Availability and implementation

CNN-PepPred is freely available as a Python tool with a detailed User's Guide at: https://github.com/ComputBiol-IBB/CNN-PepPred.

Supplementary information

Supplementary data are available at Bioinformatics online.

SUBMITTER: Junet V 

PROVIDER: S-EPMC8652105 | biostudies-literature |

REPOSITORIES: biostudies-literature

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