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Repurposing an Antiviral Drug against SARS-CoV-2 Main Protease.

ABSTRACT: This article highlights recent pioneering work by Günther et al. towards the discovery of potential repurposed antiviral compounds (peptidomimetic and non-peptidic) against the SARS-CoV-2 main protease (Mpro ). The antiviral activity of the most potent drugs is discussed along with their binding mode to Mpro as observed through X-ray crystallographic screening.

SUBMITTER: Sarkar A 

PROVIDER: S-EPMC8652770 | biostudies-literature |

REPOSITORIES: biostudies-literature

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