Effect of Hydrocortisone on Intradialytic Hypotension: A Preliminary Investigational Study.

ABSTRACT:

Introduction

Approximately 15 to 33% of all dialysis treatments are complicated by intradialytic hypotension (IDH). In this study, we tested the hypothesis that the intravenous administration of hydrocortisone prior to HD treatment could prevent IDH or at least decrease the drop in the blood pressure resulting from IDH.

Methods

This study was approved by our local ethics committee/IRB (2017/87) and by the Jordan Food and Drug Administration (7/clinical/18). Additionally, it is registered on ClinicalTrials.gov (NCT03465007). In this preliminary investigational study, we screened all chronic hemodialysis patients at our clinic who were 18 years of age or older (n = 82) for IDH. There were 14 patients included in the interventional part of this study; patients were given

SUBMITTER: Alhawari HH 

PROVIDER: S-EPMC8654564 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature