Total synthesis of remdesivir.
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ABSTRACT:
SUBMITTER: Kumar Palli K
PROVIDER: S-EPMC8656175 | biostudies-literature | 2022 Jan
REPOSITORIES: biostudies-literature
Publications
Total synthesis of remdesivir.
Kumar Palli Kishore K Ghosh Palash P Krishna Avula Shiva S Sridhara Shanmukha Rao B B Patil Amol D AD Ghosh Subhash S Sudhakar Gangarajula G Raji Reddy Chada C Mainkar Prathama S PS Chandrasekhar Srivari S
Tetrahedron letters 20211209
Remdesivir, the first drug approved by the FDA to treat COVID-19, is in high demand for patients infected with the SARS-CoV-2 virus. Herein, we report a facile approach minimizing the protecting group manipulations to afford remdesivir in good overall yield. ...[more]
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