Ontology highlight
ABSTRACT:
SUBMITTER: Papanota AM
PROVIDER: S-EPMC8658678 | biostudies-literature | 2021 Dec
REPOSITORIES: biostudies-literature
Papanota Aristea-Maria AM Karousi Paraskevi P Kontos Christos K CK Artemaki Pinelopi I PI Liacos Christine-Ivy CI Papadimitriou Maria-Alexandra MA Bagratuni Tina T Eleutherakis-Papaiakovou Evangelos E Malandrakis Panagiotis P Ntanasis-Stathopoulos Ioannis I Gavriatopoulou Maria M Kastritis Efstathios E Avgeris Margaritis M Dimopoulos Meletios-Athanasios MA Scorilas Andreas A Terpos Evangelos E
International journal of molecular sciences 20211205 23
Multiple myeloma (MM) is the second most common hematological malignancy, arising from terminally differentiated B cells, namely plasma cells. miRNAs are small non-coding RNAs that participate in the post-transcriptional regulation of gene expression. In this study, we investigated the role of nine miRNAs in MM. CD138+ plasma cells were selected from bone marrow aspirates from MM and smoldering MM (sMM) patients. Total RNA was extracted and in vitro polyadenylated. Next, first-strand cDNA synthe ...[more]