Ontology highlight
ABSTRACT:
SUBMITTER: Zhang Y
PROVIDER: S-EPMC8659241 | biostudies-literature | 2021 Dec
REPOSITORIES: biostudies-literature
Zhang Yan Y Qiu Zhidong Z Zhu Ming M Teng Ye Y
Molecules (Basel, Switzerland) 20211203 23
Ginsenoside compound K (CK) is one of the major metabolites of the bioactive ingredients in <i>Panax ginseng</i>, which presents excellent bioactivity and regulates the expression of important proteins. In this work, the effects of CK on G-quadruplexes (G4s) were quantitatively analyzed in the presence and absence of their complementary sequences. CK was demonstrated to facilitate the formation of G4s, and increase the quantity of G4s in the competition with duplex. Thermodynamic experiments sug ...[more]