Ontology highlight
ABSTRACT:
SUBMITTER: Mary C
PROVIDER: S-EPMC8660882 | biostudies-literature | 2021 Dec
REPOSITORIES: biostudies-literature
Mary Charline C Fouillen Aurélien A Moffatt Pierre P Guadarrama Bello Dainelys D Wazen Rima M RM Grenier Daniel D Nanci Antonio A
Scientific reports 20211209 1
The mouth environment comprises the second most significant microbiome in the body, and its equilibrium is critical in oral health. Secretory calcium-binding phosphoprotein proline-glutamine rich 1 (SCPPPQ1), a protein normally produced by the gingival epithelium to mediate its attachment to teeth, was suggested to be bactericidal. Our aim was to further explore the antibacterial potential of human SCPPPQ1 by characterizing its mode of action and identifying its active portions. In silico analys ...[more]