Adverse Pregnancy Outcomes and Incident Heart Failure in the Women's Health Initiative.

ABSTRACT:

Importance

Some prior evidence suggests that adverse pregnancy outcomes (APOs) may be associated with heart failure (HF). Identifying unique factors associated with the risk of HF and studying HF subtypes are important next steps.

Objective

To investigate the association of APOs with incident HF overall and stratified by HF subtype (preserved vs reduced ejection fraction) among postmenopausal women in the Women's Health Initiative (WHI).

Design, setting, and participants

In 2017, an APO history survey was administered in the WHI study, a large multiethnic cohort of postmenopausal women. The associations of 5 APOs (gestational diabetes, hypertensive disorders of pregnancy [HDP], low birth weight, high birth weight, and preterm delivery) with incident adjudicated HF wer

SUBMITTER: Hansen AL 

PROVIDER: S-EPMC8662370 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature