A single motor neuron determines the rhythm of early motor behavior in Ciona.
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ABSTRACT:
SUBMITTER: Akahoshi T
PROVIDER: S-EPMC8664258 | biostudies-literature | 2021 Dec
REPOSITORIES: biostudies-literature
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A single motor neuron determines the rhythm of early motor behavior in <i>Ciona</i>.
Akahoshi Taichi T Utsumi Madoka K MK Oonuma Kouhei K Murakami Makoto M Horie Takeo T Kusakabe Takehiro G TG Oka Kotaro K Hotta Kohji K
Science advances 20211210 50
Recent work in tunicate supports the similarity between the motor circuits of vertebrates and basal deuterostome lineages. To understand how the rhythmic activity in motor circuits is acquired during development of protochordate <i>Ciona</i>, we investigated the coordination of the motor response by identifying a single pair of oscillatory motor neurons (MN2/A10.64). The MN2 neurons had Ca<sup>2+</sup> oscillation with an ~80-s interval that was cell autonomous even in a dissociated single cell. ...[more]
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