Ontology highlight
ABSTRACT:
SUBMITTER: Stokes AM
PROVIDER: S-EPMC8669280 | biostudies-literature | 2021 Dec
REPOSITORIES: biostudies-literature
Stokes Ashley M AM Bergamino Maurizio M Alhilali Lea L Hu Leland S LS Karis John P JP Baxter Leslie C LC Bell Laura C LC Quarles C Chad CC
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20210820 12
Relative cerebral blood volume (rCBV) obtained from dynamic susceptibility contrast (DSC) MRI is adversely impacted by contrast agent leakage in brain tumors. Using simulations, we previously demonstrated that multi-echo DSC-MRI protocols provide improvements in contrast agent dosing, pulse sequence flexibility, and rCBV accuracy. The purpose of this study is to assess the <i>in-vivo</i> performance of dual-echo acquisitions in patients with brain tumors (n = 59). To verify pulse sequence flexib ...[more]