Ontology highlight
ABSTRACT:
SUBMITTER: Bischoff P
PROVIDER: S-EPMC8677623 | biostudies-literature | 2021 Dec
REPOSITORIES: biostudies-literature
Bischoff Philip P Trinks Alexandra A Obermayer Benedikt B Pett Jan Patrick JP Wiederspahn Jennifer J Uhlitz Florian F Liang Xizi X Lehmann Annika A Jurmeister Philipp P Elsner Aron A Dziodzio Tomasz T Rückert Jens-Carsten JC Neudecker Jens J Falk Christine C Beule Dieter D Sers Christine C Morkel Markus M Horst David D Blüthgen Nils N Klauschen Frederick F
Oncogene 20211018 50
Recent developments in immuno-oncology demonstrate that not only cancer cells, but also the tumor microenvironment can guide precision medicine. A comprehensive and in-depth characterization of the tumor microenvironment is challenging since its cell populations are diverse and can be important even if scarce. To identify clinically relevant microenvironmental and cancer features, we applied single-cell RNA sequencing to ten human lung adenocarcinomas and ten normal control tissues. Our analyses ...[more]