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Poly(ethylene glycol) dimethyl ether mediated oxidative scission of aromatic olefins to carbonyl compounds by molecular oxygen.

ABSTRACT: A simple, and practical oxidative scission of aromatic olefins to carbonyl compounds using O₂ as the sole oxidant with poly(ethylene glycol) dimethyl ether as a benign solvent has been developed. A wide range of monosubstituted, gem-disubstituted, 1,2-disubstituted, trisubstituted and tetrasubstituted aromatic olefins was successfully converted into the corresponding aldehydes and ketones in excellent yields even with gram-scale reaction. Some control experiments were also conducted to support a possible reaction pathway.

SUBMITTER: Yu T

PROVIDER: S-EPMC8697527 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature

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Poly(ethylene glycol) dimethyl ether mediated oxidative scission of aromatic olefins to carbonyl compounds by molecular oxygen.

Yu Tao T Guo Mingqing M Wen Simiaomiao S Zhao Rongrong R Wang Jinlong J Sun Yanli Y Liu Qixing Q Zhou Haifeng H

RSC advances 20210414 23

A simple, and practical oxidative scission of aromatic olefins to carbonyl compounds using O<sub>2</sub> as the sole oxidant with poly(ethylene glycol) dimethyl ether as a benign solvent has been developed. A wide range of monosubstituted, <i>gem</i>-disubstituted, 1,2-disubstituted, trisubstituted and tetrasubstituted aromatic olefins was successfully converted into the corresponding aldehydes and ketones in excellent yields even with gram-scale reaction. Some control experiments were also cond ...[more]

PMID: 35423908

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