Premature ventricular complexes and development of heart failure in a community-based population.

ABSTRACT:

Objective

A higher premature ventricular complex (PVC) frequency is associated with incident congestive heart failure (CHF) and death. While certain PVC characteristics may contribute to that risk, the current literature stems from patients in medical settings and is therefore prone to referral bias. This study aims to identify PVC characteristics associated with incident CHF in a community-based setting.

Methods

The Cardiovascular Health Study is a cohort of community-dwelling individuals who underwent prospective evaluation and follow-up. We analysed 24-hour Holter data to assess PVC characteristics and used multivariable logistic and Cox proportional hazards models to identify predictors of a left ventricular ejection fraction (LVEF) decline and incident CHF, respectively

SUBMITTER: Limpitikul WB 

PROVIDER: S-EPMC8702448 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature