Ontology highlight
ABSTRACT:
SUBMITTER: Kenet G
PROVIDER: S-EPMC8705574 | biostudies-literature | 2021 Dec
REPOSITORIES: biostudies-literature
Kenet Gili G Chen Yeu-Chin YC Lowe Gillian G Percy Charles C Tran Huyen H von Drygalski Annette A Trossaërt Marc M Reding Mark M Oldenburg Johannes J Mingot-Castellano Maria Eva ME Park Young-Shil YS Peyvandi Flora F Ozelo Margareth C MC Mahlangu Johnny J Quinn Jennifer J Huang Mei M Reddy Divya B DB Kim Benjamin B
Journal of clinical medicine 20211218 24
Regular prophylaxis with exogenous factor VIII (FVIII) is recommended for individuals with severe haemophilia A (HA), but standardised data are scarce. Here, we report real-world data from a global cohort. Participants were men ≥18 years old with severe HA (FVIII ≤ 1 IU/dL) receiving regular prophylaxis with FVIII. Participants provided 6 months of retrospective data and were prospectively followed for up to 12 months. Annualised bleeding rate (ABR) and FVIII utilisation and infusion rates were ...[more]