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Exploring the Phytochemicals of Acacia melanoxylon R. Br.


ABSTRACT: Invasive species are currently a world menace to the environment, although the study of their chemistry may provide a means for their future beneficial use. From a study of Portuguese Acacia melanoxylon R. Br. five known compounds were isolated: lupeol, 3β-Z-coumaroyl lupeol, 3β-E-coumaroyl lupeol (dioslupecin A), kolavic acid 15-methyl ester and vomifoliol (blumenol A). Their structures were elucidated by 1D and 2D NMR spectroscopy and mass spectrometry, and as a result some corrections are made to their previous 13C NMR assignments. Cytotoxicity of 3β-E-coumaroyl lupeol (dioslupecin A) and kolavic acid 15-methyl ester was evaluated against HCT116 human colorectal cancer cells although biological activity was not evident.

SUBMITTER: Alves D 

PROVIDER: S-EPMC8706220 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature

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Exploring the Phytochemicals of <i>Acacia melanoxylon</i> R. Br.

Alves Diana D   Duarte Sidónio S   Arsénio Pedro P   Gonçalves Joana J   Rodrigues Cecília M P CMP   Lourenço Ana A   Máximo Patrícia P  

Plants (Basel, Switzerland) 20211208 12


Invasive species are currently a world menace to the environment, although the study of their chemistry may provide a means for their future beneficial use. From a study of Portuguese <i>Acacia melanoxylon</i> R. Br. five known compounds were isolated: lupeol, 3β-<i>Z</i>-coumaroyl lupeol, 3β-<i>E</i>-coumaroyl lupeol (dioslupecin A), kolavic acid 15-methyl ester and vomifoliol (blumenol A). Their structures were elucidated by 1D and 2D NMR spectroscopy and mass spectrometry, and as a result som  ...[more]

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