Triterpene Glycosides from the Far Eastern Sea Cucumber Psolus chitonoides: Chemical Structures and Cytotoxicities of Chitonoidosides E₁, F, G, and H.

ABSTRACT: Four new triterpene disulfated glycosides, chitonoidosides E₁ (1), F (2), G (3), and H (4), were isolated from the Far-Eastern sea cucumber Psolus chitonoides and collected near Bering Island (Commander Islands) at depths of 100-150 m. Among them there are two hexaosides (1 and 3), differing from each other by the terminal (sixth) sugar residue, one pentaoside (4) and one tetraoside (2), characterized by a glycoside architecture of oligosaccharide chains with shortened bottom semi-chains, which is uncommon for sea cucumbers. Some additional distinctive structural features inherent in 1-4 were also found: the aglycone of a recently discovered new type, with 18(20)-ether bond and lacking a lactone in chit

SUBMITTER: Silchenko AS 

PROVIDER: S-EPMC8708177 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature