Impact of Circadian Desynchrony on Spermatogenesis: A Mini Review.
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ABSTRACT:
SUBMITTER: Fusco F
PROVIDER: S-EPMC8717881 | biostudies-literature | 2021
REPOSITORIES: biostudies-literature
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Impact of Circadian Desynchrony on Spermatogenesis: A Mini Review.
Fusco Ferdinando F Longo Nicola N De Sio Marco M Arcaniolo Davide D Celentano Giuseppe G Capece Marco M La Rocca Roberto R Mangiapia Francesco F Califano Gianluigi G Morra Simone S Turco Carmine C Spena Gianluca G Spirito Lorenzo L Fusco Giovanni Maria GM Cirillo Luigi L De Luca Luigi L Napolitano Luigi L Mirone Vincenzo V Creta Massimiliano M
Frontiers in endocrinology 20211216
The purpose of this mini review is to provide data about pre-clinical and clinical evidence exploring the impact of circadian desynchrony on spermatogenesis. Several lines of evidence exist demonstrating that disruption of circadian rhythms may interfere with male fertility. Experimental knock-out or knock-down of clock genes, physiologically involved in the regulation of circadian rhythms, are associated with impairments of fertility pathways in both animal and human models. Moreover, disruptio ...[more]
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