Resveratrol has an Overall Neuroprotective Role in Ischemic Stroke: A Meta-Analysis in Rodents.

ABSTRACT: Background: Resveratrol, a natural polyphenolic phytoalexin, is broadly presented in dietary sources. Previous research has suggested its potential neuroprotective effects on ischemic stroke animal models. However, these results have been disputable. Here, we conducted a meta-analysis to comprehensively evaluate the effect of resveratrol treatment in ischemic stroke rodent models. Objective: To comprehensively evaluate the effect of resveratrol treatment in ischemic stroke rodent models. Methods: A literature search of the databases Pubmed, Embase, and Web of science identified 564 studies that were subjected to pre-defined inclusion criteria. 54 studies were included and analyzed using a random-effects model to calculate the standardized mean difference (SMD) with cor

SUBMITTER: Liu J 

PROVIDER: S-EPMC8721173 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature