COVID-19 Outcomes and Genomic Characterization of SARS-CoV-2 Isolated From Veterans in New England States: Retrospective Analysis.

ABSTRACT:

Background

Clinical and virologic characteristics of COVID-19 infections in veterans in New England have not been described. The average US veteran is a male older than the general US population. SARS-CoV-2 infection is known to cause poorer outcomes among men and older adults, making the veteran population an especially vulnerable group for COVID-19.

Objective

This study aims to evaluate clinical and virologic factors impacting COVID-19 outcomes.

Methods

This retrospective chart review included 476 veterans in six New England states with confirmed SARS-CoV-2 infection between April and September 2020. Whole genome sequencing was performed on SARS-CoV-2 RNA isolated from these veterans, and the correlation of genomic data to clinical outcomes was evaluated. Clinical a

SUBMITTER: Lee M 

PROVIDER: S-EPMC8722526 | biostudies-literature | 2021 Oct-Dec

REPOSITORIES: biostudies-literature