Microtubule affinity regulating kinase 4 promoted activation of the NLRP3 inflammasome-mediated pyroptosis in periodontitis
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ABSTRACT: Background
Microtubule dynamics plays a crucial role in the spatial arrangement of cell organelles and activation of the NLRP3 inflammasome. Purpose
This study aimed to explore whether microtubule affinity regulating kinase 4 (MARK4) can be a therapeutic target of periodontitis by affecting microtubule dynamics and NLRP3 inflammasome-mediated pyroptosis in macrophages. Materials and Methods
The NLRP3 inflammasome-related genes and MARK4 were measured in the healthy and inflamed
SUBMITTER: Wang L
PROVIDER: S-EPMC8725745 | biostudies-literature |
REPOSITORIES: biostudies-literature
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