Unknown

Dataset Information

0

SARS-CoV-2 Omicron RBD shows weaker binding affinity than the currently dominant Delta variant to human ACE2.

ABSTRACT:

SUBMITTER: Wu L 

PROVIDER: S-EPMC8727475 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature

Json Xml
altmetric image

Publications

SARS-CoV-2 Omicron RBD shows weaker binding affinity than the currently dominant Delta variant to human ACE2.

Wu Leyun L   Zhou Liping L   Mo Mengxia M   Liu Tingting T   Wu Chengkun C   Gong Chunye C   Lu Kai K   Gong Likun L   Zhu Weiliang W   Xu Zhijian Z  

Signal transduction and targeted therapy 20220105 1

Similar Datasets

Unknown Scanning the RBD-ACE2 molecular interactions in Omicron variant.
| S-EPMC8732900 | biostudies-literature
Unknown Molecular dynamic simulation suggests stronger interaction of Omicron-spike with ACE2 than wild but weaker than Delta SARS-CoV-2 can be blocked by engineered S1-RBD fraction.
| S-EPMC9362541 | biostudies-literature
Unknown Reversal of the unique Q493R mutation increases the affinity of Omicron S1-RBD for ACE2.
| S-EPMC10006685 | biostudies-literature
Unknown Omicron SARS-CoV-2 Variant Spike Protein Shows an Increased Affinity to the Human ACE2 Receptor: An In Silico Analysis.
| S-EPMC8779645 | biostudies-literature
Unknown Effect of Delta and Omicron Mutations on the RBD-SD1 Domain of the Spike Protein in SARS-CoV-2 and the Omicron Mutations on RBD-ACE2 Interface Complex.
| S-EPMC9456519 | biostudies-literature
Unknown Change in binding affinity with ACE2 receptor in beta, delta and omicron SARS CoV2 variants.
| S-EPMC9123474 | biostudies-literature
Unknown Receptor binding and complex structures of human ACE2 to spike RBD from omicron and delta SARS-CoV-2.
| S-EPMC8733278 | biostudies-literature
Unknown Structural basis of human ACE2 higher binding affinity to currently circulating Omicron SARS-CoV-2 sub-variants BA.2 and BA.1.1.
| S-EPMC9212699 | biostudies-literature
Unknown Structural insights into the SARS-CoV-2 Omicron RBD-ACE2 interaction.
| S-EPMC9007263 | biostudies-literature
Unknown Impact of African-Specific ACE2 Polymorphisms on Omicron BA.4/5 RBD Binding and Allosteric Communication Within the ACE2-RBD Protein Complex.
| S-EPMC11818624 | biostudies-literature