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Unraveling the publication trends in inhalable nano-systems.

ABSTRACT: Nano-systems (size range: 1 ~ 1000 nm) have been widely investigated as pulmonary drug delivery carriers, and the safety of inhaled nano-systems has aroused general interests. In this work, bibliometric analysis was performed to describe the current situation of related literature, figure out the revolutionary trends, and eventually forecast the possible future directions. The relevant articles and reviews from 2001 to 2020 were retrieved from the Web of Science Core Collection. The documents were processed by Clarivate Analytic associated with Web of Science database, Statistical Analysis Toolkit for Informetric, bibliometric online platform and VOSviewer, and the data were visualized. The bibliometric overview of the literature was described, citation analysis was performed, and research hotspots were showcased. The bibliometric analysis of 3362 documents of interest indicated that most of the relevant source titles were in the fields of toxicology, pharmacy, and materials science. The three research hotspots were the biological process of inhalable nano-systems in vivo, the manufacture of inhalable nano-systems, and the impact of nano-systems on human health in the environment. Toxicity and safety have always been the keywords. The USA was the major contributing country, and international collaboration and co-authorship were common phenomena. The general situation and development trend of literature of inhalable nano-systems were summarized. It was anticipated that bibliometrics analysis could provide new ideas for the future research of inhalable nano-systems.

Supplementary information

The online version contains supplementary material available at 10.1007/s11051-021-05384-1.

SUBMITTER: Huang Z

PROVIDER: S-EPMC8739024 | biostudies-literature |

REPOSITORIES: biostudies-literature

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Project description:PurposeIn this investigation, we aimed to describe trends in time to acceptance (TTA) and time to online publication (TTOP) of research published in leading radiation oncology journals from 2010 to 2019. We further sought to identify journal characteristics that might influence TTA and TTOP.Methods and materialsWe searched the publication history of 5 leading international radiation oncology journals. For all research articles accepted from January 1, 2010, to December 31, 2019, we tabulated the date of article receipt, the date of acceptance, and the date of online publication when available. The TTA was calculated as the number of elapsed days from article receipt to acceptance, and the TTOP was calculated as the number of elapsed days from article acceptance to online publication. Using the Mann-Kendall test, we assessed for monotonic trends over time and used the post hoc Theil-Sen method to estimate rates of change. We created a multiple regression model to identify journal characteristics associated with TTA and TTOP.ResultsIn total, 10,132 articles were included. Both the TTA and the TTOP decreased significantly from 2010 to 2019 (P = .005 and P < .001, respectively), with an estimated decrease of 1.5 days per year for the TTA and 7.0 days per year for the TTOP. Multiple regression modeling revealed that a higher journal impact factor was independently associated with an increased TTA (P < .001) and a decreased TTOP (P < .001). A higher number of accepted journal articles per year was associated with a decreased TTA (P < .001) and an increased TTOP (P < .001).ConclusionsRadiation oncology research has been accepted and published online at increasingly faster rates during the past decade. The TTA may be longer in higher-impact, more selective journals, possibly suggesting a need for comprehensive peer review and complex editorial decisions. However, these articles are also published online faster after article acceptance. Future work examining patterns of acceptance and publication speed is needed to encourage rapid dissemination of practice-guiding data.

Project description:BackgroundWe previously demonstrated that in a Japanese national university's medical faculty, overall paper publication frequency increased between 1979-1980 and 2017-2018, while original paper publication did not increase. Further, publication language changed from predominantly Japanese to English. However, whether these trends are specific to medicine or representative of other faculties remains unclear.MethodsWe diachronically analyzed annual university library-produced publication reports for four pharmaceutical and three medical units between 1979-1980 and 2019-2020, elucidating how publication frequency, type, and language medium changed.ResultsAll publication types increased for the pharmaceutical faculty, from 2.87 per faculty member per year to 10.77. Publication of original papers more than doubled, from 1.06 per faculty member per year to 2.37. This increase was exclusively in English publication, with no publication of Japanese original papers in 2019-2020. This contrasts with medicine, which, while it demonstrated similar increases in all publication types combined, from 4.92 papers per faculty member per year to 12.78, did not demonstrate as striking an increase in total original paper publication (English and Japanese), from 1.21 papers per faculty member per year to 1.30. However, these two faculties observed similar trends in that English largely replaced Japanese original paper publication. That both faculties' Japanese original paper publication decreased suggests English language original paper publication comes at the expense of publishing in Japanese. Concerning both faculties together, the increase in publishing frequency for all publication types more than tripled from 4.01 to 12.38. This was largely driven by changes in conference paper publication for the pharmaceutical sciences faculty, where English publication increased 2,775% (0.06 to 1.7 papers per faculty member per year) and Japanese language publication 258% (1.33 to 4.77). While conference paper publication did increase for the medical sciences, its change in total publication frequency was largely driven by 'other' types of publication, which increased from 0.51 publications per faculty member per year in 1979-1980 to 5.41 in 2019-2020, largely driven by Japanese language publication.ConclusionIn 2019-2020, pharmaceutical sciences faculty members largely published original papers in English, so postgraduate education should consider the future likelihood of graduates needing to publish in English.

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Unraveling the publication trends in inhalable nano-systems.

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