Ontology highlight
ABSTRACT:
SUBMITTER: Semerdzhiev SA
PROVIDER: S-EPMC8739828 | biostudies-literature | 2022 Jan
REPOSITORIES: biostudies-literature
Semerdzhiev Slav A SA Fakhree Mohammad A A MAA Segers-Nolten Ine I Blum Christian C Claessens Mireille M A E MMAE
ACS chemical neuroscience 20211203 1
First cases that point at a correlation between SARS-CoV-2 infections and the development of Parkinson's disease (PD) have been reported. Currently, it is unclear if there is also a direct causal link between these diseases. To obtain first insights into a possible molecular relation between viral infections and the aggregation of α-synuclein protein into amyloid fibrils characteristic for PD, we investigated the effect of the presence of SARS-CoV-2 proteins on α-synuclein aggregation. We show, ...[more]