Ontology highlight
ABSTRACT:
SUBMITTER: Ma D
PROVIDER: S-EPMC8740452 | biostudies-literature | 2021 Dec
REPOSITORIES: biostudies-literature
Ma Dumei D Zhang Libo L Yin Yingwu Y Gao Yuxing Y Wang Qian Q
Journal of pharmaceutical analysis 20201221 6
P450 fatty acid decarboxylase OleT from <i>Staphylococcus aureus</i> (OleT<sub>SA</sub>) is a novel cytochrome P450 enzyme that catalyzes the oxidative decarboxylation of fatty acids to yield primarily terminal alkenes and CO<sub>2</sub> or minor α- and β-hydroxylated fatty acids as side-products. In this work, the interactions between a series of cycloalkyl phosphorus heterocycles (CPHs) and OleT<sub>SA</sub> were investigated in detail by fluorescence titration experiment, ultraviolet-visible ...[more]