Unknown

Dataset Information

0

Supervised learning model predicts protein adsorption to carbon nanotubes.


ABSTRACT: [Figure: see text].

SUBMITTER: Ouassil N 

PROVIDER: S-EPMC8741178 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature

altmetric image

Publications

Supervised learning model predicts protein adsorption to carbon nanotubes.

Ouassil Nicholas N   Pinals Rebecca L RL   Del Bonis-O'Donnell Jackson Travis JT   Wang Jeffrey W JW   Landry Markita P MP  

Science advances 20220107 1


Engineered nanoparticles are advantageous for biotechnology applications including biomolecular sensing and delivery. However, testing compatibility and function of nanotechnologies in biological systems requires a heuristic approach, where unpredictable protein corona formation prevents their effective implementation. We develop a random forest classifier trained with mass spectrometry data to identify proteins that adsorb to nanoparticles based solely on the protein sequence (78% accuracy, 70%  ...[more]

Similar Datasets

| S-EPMC4204026 | biostudies-literature
2024-09-14 | PXD011354 | Pride
| S-EPMC4758076 | biostudies-literature
| S-EPMC4737755 | biostudies-literature
| S-EPMC5459067 | biostudies-other
| S-EPMC3033603 | biostudies-literature
| S-EPMC3936481 | biostudies-literature
| S-EPMC3380380 | biostudies-literature
| S-EPMC10304972 | biostudies-literature
| S-EPMC7797377 | biostudies-literature