Ontology highlight
ABSTRACT:
SUBMITTER: Ferrucci PF
PROVIDER: S-EPMC8750474 | biostudies-literature | 2021 Dec
REPOSITORIES: biostudies-literature
Ferrucci Pier Francesco PF Cocorocchio Emilia E
Cancers 20211224 1
Immunotherapy with Ipilimumab or antibodies against programmed death (ligand) 1 (anti-PD1/PDL1), targeted therapies with BRAF-inhibitors (anti-BRAF) and their combinations significantly changed melanoma treatment options in both primary, adjuvant and metastatic setting, allowing for a cure, or at least long-term survival, in most patients. However, up to 50% of those with advance or metastatic disease still have no significant benefit from such innovative therapies, and clinicians are not able t ...[more]