Ontology highlight
ABSTRACT:
SUBMITTER: Mammoser CC
PROVIDER: S-EPMC8750573 | biostudies-literature | 2021 Jun
REPOSITORIES: biostudies-literature
Mammoser Claire C CC Ramos Sashary S Thielges Megan C MC
Biochemistry 20210518 21
Cytochrome P450s are diverse and powerful catalysts that can activate molecular oxygen to oxidize a wide variety of substrates. Catalysis relies on effective uptake of two electrons and two protons. For cytochrome P450cam, an archetypal member of the superfamily, the second electron must be supplied by the redox partner putidaredoxin (Pdx). Pdx also plays an effector role beyond electron transfer, but after decades the mechanism remains under investigation. We applied infrared spectroscopy to he ...[more]