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Increased Risk of Velopharyngeal Insufficiency in Patients Undergoing Staged Palate Repair.


ABSTRACT:

Objective

To evaluate the association of 2-stage cleft palate (CP) surgery on velopharyngeal insufficiency (VPI) incidence, speech surgeries, and cleft-related surgical burden.

Design

Retrospective cohort with follow-up of 4 to 19 years.

Setting

Academic, tertiary children's hospital.

Patients

Patients who underwent CP surgery between 2000 and 2017. Exclusions included submucous CP or age at last contact under 3.9.

Interventions

Cleft palate surgery, completed in either a single-stage or 2-stage repair.

Main outcome measure(s)

Rates of VPI diagnosis and speech surgery and total cleft surgeries; t tests, tests of proportion, and linear and logistic regression were performed. Total cleft-related surgeries were examined in a subset (n = 418) of patients with chart reviews.

Results

A total of 1047 patients were included; 59.6% had 2-stage CP repair, 40.4% had single-stage repair. Approximately 32% of children with 2-stage CP repair were diagnosed with VPI, as opposed to 22% of single-stage patients (P < .001). Children with 2-stage CP repair were 1.8 times as likely to be diagnosed with VPI (P < .001). Speech surgery rates were similar across groups. Patients who had 2-stage repair received an average of 2.3 more cleft-related procedures, when excluding prosthesis management procedures.

Conclusion

Our data show an increased risk of VPI diagnosis and increased surgical burden among patients receiving 2-stage CP repair.

SUBMITTER: McCrary H 

PROVIDER: S-EPMC8751621 | biostudies-literature |

REPOSITORIES: biostudies-literature

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