Effect of a low-salt diet on chronic kidney disease outcomes: a systematic review and meta-analysis.

ABSTRACT:

Objective

The benefits of a low-salt diet for patients with chronic kidney disease (CKD) are controversial. We conducted a systematic review and meta-analysis of the effect of a low-salt diet on major clinical outcomes.

Design

Systematic review and meta-analysis.

Data sources

MEDLINE by Ovid, EMBASE and the Cochrane Library databases.

Eligibility criteria for selecting studies

We included randomised controlled trials (RCTs) and cohort studies that assessed the effect of a low-salt diet on the renal composite outcomes (more than 50% decline in estimated glomerular filtration rate (eGFR) during follow-up, doubling of serum creatinine or end-stage renal disease), rate of eGFR decline, change in proteinuria, all-cause mortality events, cardiovascular (CV) events, a

SUBMITTER: Shi H 

PROVIDER: S-EPMC8753423 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature